Peripheral tolerance of Th2 lymphocytes induced by continuous feeding of ovalbumin

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Peripheral tolerance of Th2 lymphocytes induced by continuous feeding of ovalbumin.

We established conditions for inducing antigen-specific tolerance in Th2 lymphocytes by means of oral tolerance. Mice were continuously exposed to ovalbumin in their drinking water for a minimal period of 20 days and then immunized against antigen in either complete Freund's adjuvant or Al(OH)3. This feeding regimen tolerized both Th2 and Th1 responses as shown by diminished proliferation, cyto...

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ژورنال

عنوان ژورنال: International Immunology

سال: 1996

ISSN: 0953-8178,1460-2377

DOI: 10.1093/intimm/8.5.717